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href=\"https:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/0000068484.html\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/0000068484.html<\/a>\uff09\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p><h2 class=\"wp-block-heading\"><strong>\u25a0Pitolisant\u306b\u3064\u3044\u3066<\/strong><\/h2><p>Pitolisant\u306f\u3001\u4eba\u9593\u306e\u7761\u7720\u30fb\u899a\u9192\u30ea\u30ba\u30e0\u306e\u5236\u5fa1\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u308b\u30d2\u30b9\u30bf\u30df\u30f3\u542b\u6709\u30cb\u30e5\u30fc\u30ed\u30f3\u306e\u30b7\u30ca\u30d7\u30b9\u524d\u90e8\u306b\u5206\u5e03\u3059\u308b\u81ea\u5df1\u53d7\u5bb9\u4f53\u3001\u30d2\u30b9\u30bf\u30df\u30f3H3\u53d7\u5bb9\u4f53\u3078\u9078\u629e\u7684\u306b\u7d50\u5408\u3059\u308b\u62ee\u6297\u85ac\/\u9006\u4f5c\u52d5\u85ac\u3067\u3059\u3002pitolisant\u306f\u3001Bioprojet\uff08\u30d5\u30e9\u30f3\u30b9\u3001\u30d1\u30ea\u5e02\uff09\u306b\u3088\u308a\u5275\u85ac\u3055\u308c\u3001\u6b27\u5dde\u3067\u306f2016\u5e74\u306b\u300c\u30ab\u30bf\u30d7\u30ec\u30ad\u30b7\u30fc\uff08\u60c5\u52d5\u8131\u529b\u767a\u4f5c\uff09\u3092\u4f34\u3046\u3001\u53c8\u306f\u4f34\u308f\u306a\u3044\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u300d\u3092\u52b9\u80fd\u30fb\u52b9\u679c\u3068\u3057\u3066\u30012021\u5e74\u306b\u306f\u300c\u9589\u585e\u6027\u7761\u7720\u6642\u7121\u547c\u5438\u75c7\u5019\u7fa4\uff08OSAS\uff09\u60a3\u8005\u306b\u304a\u3051\u308b\u899a\u9192\u72b6\u614b\u306e\u6539\u5584\u53ca\u3073\u65e5\u4e2d\u306e\u904e\u5ea6\u306e\u7720\u6c17\u306e\u6e1b\u5c11\u300d\u3092\u8ffd\u52a0\u306e\u52b9\u80fd\u30fb\u52b9\u679c\u3068\u3057\u3066\u6b27\u5dde\u533b\u85ac\u54c1\u5e81\uff08EMA\uff09\u3088\u308a\u627f\u8a8d\u53d6\u5f97\u3057\u307e\u3057\u305f\u3002\u7c73\u56fd\u3067\u306f2019\u5e74\u306b\u300c\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u306b\u4f34\u3046\u65e5\u4e2d\u306e\u904e\u5ea6\u306e\u7720\u6c17\u300d\u3092\u52b9\u80fd\u30fb\u52b9\u679c\u3068\u3057\u3066\u30012020\u5e74\u306b\u306f\u300c\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u306b\u4f34\u3046\u30ab\u30bf\u30d7\u30ec\u30ad\u30b7\u30fc\u300d\u3092\u8ffd\u52a0\u306e\u52b9\u80fd\u30fb\u52b9\u679c\u3068\u3057\u3066\u7c73\u56fd\u98df\u54c1\u533b\u85ac\u54c1\u5c40\uff08FDA\uff09\u3088\u308a\u627f\u8a8d\u3092\u53d6\u5f97\u3057\u3066\u304a\u308a\u3001\u65e2\u306b\u81e8\u5e8a\u73fe\u5834\u3067\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u30022023\u5e74\u672b\u6642\u70b9\u3067\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u306b\u3064\u3044\u3066\u306f\u6b27\u5dde\u30fb\u7c73\u56fd\u542b\u308138\u304b\u56fd\u3001OSAS\u306b\u3064\u3044\u3066\u306f\u6b27\u5dde30\u304b\u56fd\u3067\u627f\u8a8d\u3092\u5f97\u3066\u304a\u308a\u307e\u3059\u3002<\/p><h2 class=\"wp-block-heading\"><strong>\u25a0\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u306b\u3064\u3044\u3066<\/strong><\/h2><p>\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u306e\u767a\u75c7\u6642\u671f\u306f\u5c0f\u5150\u671f\u3001\u9752\u5e74\u671f\u304a\u3088\u3073\u82e5\u5e74\u9752\u5e74\u671f\u306b\u96c6\u4e2d\u3057\u3066\u3044\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u8aa4\u8a3a\u3055\u308c\u3084\u3059\u304f\u3001\u75c7\u72b6\u306e\u8a8d\u77e5\u5ea6\u304c\u4f4e\u3044\u305f\u3081\u306b\u78ba\u5b9a\u8a3a\u65ad\u304c\u9045\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u4e16\u754c\u7684\u306b\u8ab2\u984c\u3068\u3055\u308c\u3066\u3044\u307e\u3059<sup>1<\/sup>\u3002\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u306e\u539f\u56e0\u3084\u75c5\u614b\u306b\u3064\u3044\u3066\u306f\u672a\u3060\u89e3\u660e\u3055\u308c\u3066\u3044\u306a\u3044\u70b9\u3082\u591a\u304f\u3042\u308a\u307e\u3059\u3002\u901a\u5e38\u3001\u30aa\u30ec\u30ad\u30b7\u30f3\u3084\u30d2\u30b9\u30bf\u30df\u30f3\u306a\u3069\u306e\u8133\u5185\u306e\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u304c\u65e5\u4e2d\u306e\u899a\u9192\u3068\u591c\u9593\u306e\u7761\u7720\uff08\u30ec\u30e0\u7761\u7720\u30fb\u30ce\u30f3\u30ec\u30e0\u7761\u7720\uff09\u304c\u898f\u5247\u7684\u306b\u7e70\u308a\u8fd4\u3055\u308c\u308b\u3088\u3046\u8abf\u7bc0\u3059\u308b\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u60a3\u8005\u3055\u3093\u306b\u304a\u3044\u3066\u306f\u3053\u308c\u3089\u304c\u4e0d\u898f\u5247\u306b\u51fa\u73fe\u3057\u307e\u3059<sup>2<\/sup>\u3002\u3053\u306e\u4e0d\u898f\u5247\u306a\u7761\u7720\u30fb\u899a\u9192\u30b5\u30a4\u30af\u30eb\u306e\u305f\u3081\u3001\u5b66\u6821\u3084\u8077\u5834\u3067\u672c\u4eba\u306e\u610f\u601d\u306b\u53cd\u3057\u3066\u7720\u308a\u8fbc\u3093\u3060\u308a\u3001\u96c6\u4e2d\u529b\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u306b\u82e6\u616e\u3059\u308b\u306a\u3069\u306e\u75c7\u72b6\u304c\u307f\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u5f37\u3044\u611f\u60c5\u306e\u52d5\u304d\u3092\u304d\u3063\u304b\u3051\u3068\u3057\u3066\u5168\u8eab\u3042\u308b\u3044\u306f\u4f53\u306e\u4e00\u90e8\u306e\u968f\u610f\u7b4b\u306e\u307e\u3072\u304c\u751f\u3058\u308b\u60c5\u52d5\u8131\u529b\u767a\u4f5c\uff08\u30ab\u30bf\u30d7\u30ec\u30ad\u30b7\u30fc\uff09\u3001\u5165\u7720\u6642\u306e\u5e7b\u899a\u4f53\u9a13\uff08\u5165\u7720\u6642\u5e7b\u899a\uff09\u3084\u91d1\u7e1b\u308a\uff08\u7761\u7720\u9ebb\u75fa\uff09\u3092\u4f34\u3046\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u75c7\u72b6\u306e\u7a2e\u985e\u3084\u7a0b\u5ea6\u306f\u60a3\u8005\u3055\u3093\u3054\u3068\u306b\u7570\u306a\u308a\u307e\u3059\u304c\u3001\u5b66\u696d\u3084\u5c31\u696d\u306b\u304a\u3051\u308b\u56f0\u96e3\u306a\u3069\u3001\u60a3\u8005\u3055\u3093\u306e\u65e5\u5e38\u751f\u6d3b\u306b\u6df1\u523b\u306a\u5f71\u97ff\u3092\u3082\u305f\u3089\u3059\u5834\u5408\u304c\u3042\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059<sup>3<\/sup>\u3002<\/p><h3 class=\"wp-block-heading\"><strong>\u25a0\u30a2\u30ad\u30e5\u30ea\u30b9\u30d5\u30a1\u30fc\u30de\u682a\u5f0f\u4f1a\u793e\u306b\u3064\u3044\u3066<\/strong><\/h3><p>\u30a2\u30ad\u30e5\u30ea\u30b9\u30d5\u30a1\u30fc\u30de\u306f\u3001\u65e5\u672c\u306e\u30c9\u30e9\u30c3\u30b0\u30fb\u30e9\u30b0\uff0f\u30c9\u30e9\u30c3\u30b0\u30fb\u30ed\u30b9\u89e3\u6d88\u306e\u5148\u99c6\u8005\u3068\u306a\u308a\u795e\u7d4c\u30fb\u7cbe\u795e\u75be\u60a3\u306b\u304b\u304b\u308f\u308b\u793e\u4f1a\u8ab2\u984c\u89e3\u6c7a\u306b\u53d6\u308a\u7d44\u3080\u65e5\u672c\u767a\u306e\u88fd\u85ac\u30d9\u30f3\u30c1\u30e3\u30fc\u3067\u3059\u3002\u201cCatalyst to Access\u201d\uff08\u9769\u65b0\u7684\u306a\u533b\u7642\u3078\u306e\u6a4b\u6e21\u3057\u3092\u62c5\u3046\uff09\u3068\u3044\u3046\u7406\u5ff5\u3092\u63b2\u3052\u3001Aculys\uff08\u30a2\u30ad\u30e5\u30ea\u30b9\uff09\u3092\u793e\u540d\u3068\u3057\u307e\u3057\u305f\u3002\u795e\u7d4c\u30fb\u7cbe\u795e\u75be\u60a3\u9818\u57df\u306b\u304a\u3044\u3066\u9769\u65b0\u7684\u306a\u533b\u7642\u624b\u6bb5\u3078\u306e\u6a4b\u6e21\u3057\u5f79\u3068\u306a\u308a\u3001\u60a3\u8005\u3055\u3093\u3068\u3054\u5bb6\u65cf\u3001\u533b\u7642\u95a2\u4fc2\u8005\u3001\u793e\u4f1a\u306b\u3088\u308a\u826f\u3044\u533b\u7642\u3092\u5c4a\u3051\u308b\u305f\u3081\u3001\u6b27\u7c73\u8af8\u56fd\u304b\u3089\u9769\u65b0\u7684\u3067\u512a\u308c\u305f\u533b\u85ac\u54c1\u3092\u5c0e\u5165\u3057\u3001\u958b\u767a\u30fb\u8ca9\u58f2\u3092\u62c5\u3044\u3001\u3055\u3089\u306b\u75be\u60a3\u3092\u53d6\u308a\u5dfb\u304f\u3055\u307e\u3056\u307e\u306a\u8ab2\u984c\u306b\u5bfe\u3059\u308b\u30bd\u30ea\u30e5\u30fc\u30b7\u30e7\u30f3\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002<\/p><p>\u4f1a\u793e\u540d\uff1a\u30a2\u30ad\u30e5\u30ea\u30b9\u30d5\u30a1\u30fc\u30de\u682a\u5f0f\u4f1a\u793e \uff3b\u82f1\u8a9e\u540d\uff1aAculys Pharma, Inc. \uff3d<br \/>\u6240\u5728\u5730\uff1a\u6771\u4eac\u90fd\u6e2f\u533a\u5317\u9752\u5c712 -14 \u2013 4<br \/>\u4ee3\u8868\u8005\uff1a\u8c37\u57a3 \u4efb\u512a<br \/>\u8a2d\u7acb\u65e5\uff1a2021\u5e741\u6708<br \/>URL\uff1a<a href=\"https:\/\/aculys.com\/\">https:\/\/aculys.com<\/a><\/p><p>\uff1c\u6ce8\u610f\u4e8b\u9805\uff1e<br \/>\u672c\u30ea\u30ea\u30fc\u30b9\u306b\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\u533b\u85ac\u54c1\u306b\u95a2\u3059\u308b\u60c5\u5831\u306f\u5f53\u793e\u306e\u7d4c\u55b6\u60c5\u5831\u306e\u958b\u793a\u3092\u76ee\u7684\u3068\u3057\u3066\u304a\u308a\u3001\u5f53\u8a72\u533b\u85ac\u54c1\u306e\u5ba3\u4f1d\u30fb\u5e83\u544a\u3092\u76ee\u7684\u3068\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p><p><strong>\u51fa\u5178<\/strong>\uff1a<\/p><ol class=\"wp-block-list\"><li>Thorpy MJ, Krieger AC. Delayed diagnosis of narcolepsy: characterization and impact. 2014 May;15(5):502-7.<\/li><li>Scammell TE. Narcolepsy. NEJM. 2015;373:2654-2662.<\/li><li>Scammell TE, Jackson AC, Franks NP, Wisden W, Dauvilliers Y. Histamine: neural circuits and new medications. Sleep. 2019 Jan 1;42(1):zsy183.<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u795e\u7d4c\u30fb\u7cbe\u795e\u75be\u60a3\u9818\u57df\u306b\u304a\u3051\u308b\u9769\u65b0\u7684\u306a\u6cbb\u7642\u85ac\u306e\u958b\u767a\u3068\u5546\u696d\u5316\u3092\u63a8\u9032\u3059\u308b\u30a2\u30ad\u30e5\u30ea\u30b9\u30d5\u30a1\u30fc\u30de\u682a\u5f0f\u4f1a\u793e\uff08\u672c\u793e\uff1a\u6771\u4eac\u90fd\u6e2f\u533a\u3001\u4ee3\u8868\u53d6\u7de0\u5f79\u793e\u9577\u517cCEO\uff1a\u8c37\u57a3 \u4efb\u512a\u3001\u4ee5\u4e0b\u300c\u30a2\u30ad\u30e5\u30ea\u30b9\u30d5\u30a1\u30fc\u30de\u300d \uff09\u306f\u3001\u958b\u767a\u4e2d\u306e\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u306b\u5bfe\u3059\u308b\u30d2\u30b9\u30bf\u30df\u30f3 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":410,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[8],"tags":[],"class_list":["post-422","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-8"],"_links":{"self":[{"href":"https:\/\/accelyspharma.com\/ja\/wp-json\/wp\/v2\/posts\/422","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/accelyspharma.com\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/accelyspharma.com\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/accelyspharma.com\/ja\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/accelyspharma.com\/ja\/wp-json\/wp\/v2\/comments?post=422"}],"version-history":[{"count":0,"href":"https:\/\/accelyspharma.com\/ja\/wp-json\/wp\/v2\/posts\/422\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/accelyspharma.com\/ja\/wp-json\/wp\/v2\/media\/410"}],"wp:attachment":[{"href":"https:\/\/accelyspharma.com\/ja\/wp-json\/wp\/v2\/media?parent=422"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/accelyspharma.com\/ja\/wp-json\/wp\/v2\/categories?post=422"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/accelyspharma.com\/ja\/wp-json\/wp\/v2\/tags?post=422"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}